Anemia induces accumulation of erythropoietin mRNA in the kidney and liver.
نویسندگان
چکیده
Regulation of the production of erythropoietin occurs in the kidney and liver largely through control of accumulation of erythropoietin mRNA. Erythropoietin mRNA was first detected in kidneys at 1.5 h postanemia and reached a plateau value at least 200-fold above the control value by 4 to 8 h. A 20-base sequence immediately upstream from the reported erythropoietin mRNA initiation site is complementary to a hypervariable sequence in 18S rRNA.
منابع مشابه
پیش‌بینی مقدار تجویز داروی اریتروپویتین در بیماران همودیالیزی- رویکرد داده‌کاوی
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ورودعنوان ژورنال:
- Molecular and cellular biology
دوره 6 7 شماره
صفحات -
تاریخ انتشار 1986